Figure 7.

Anatomical accuracy of tractography is limited. (A) Region-to-region connectivity validation is shown as ROC curves for the macaque (PCG seed and V4v seed) sub-challenge and squirrel monkey (M1 seed) sub-challenge. (B) Voxel-wise spatial overlap validation is shown with plots of overlap versus overreach for the squirrel monkey sub-challenge and phantom sub-challenge (scanner A and scanner B). One marker is shown for each submission, with marker colors indicating unique research groups. A common theme in this, and other challenges, is that a specificity/sensitivity (or overlap/overreach) tradeoff is inherent in all tractography algorithms and pipelines. Reproduced and modified from Schilling et al. (2018) with permission from Elsevier.