Table 4:
In vitro soleus muscle contractile properties of skmERαWT and skmERαKO mice in study 2.
| Groups | Two-way ANOVA p-values | ||||||
|---|---|---|---|---|---|---|---|
| skmERαWT–Sed (n=6) | skmERαKO–Sed (n=5) | skmERαWT–Run (n=11) | skmERαKO–Run (n=10) | Genotype | Activity | Interaction | |
| Muscle mass (mg) | 8.22 ± 1.21 | 10.4 ± 0.95 | 10.7 ± 0.71 | 11.8 ± 1.53 | 0.003 | <0.001 | 0.283 |
| Muscle length (mm) | 10.5 ± 0.54 | 10.7 ± 0.69 | 10.3 ± 0.49 | 10.2 ± 0.35 | 0.638 | 0.114 | 0.433 |
| Physiological CSA (mm2) | 1.07 ± 0.13 | 1.29 ± 0.10 | 1.38 ± 0.11 | 1.54 ± 0.22 | 0.006 | <0.001 | 0.835 |
| Peak twitch force (mN) | 28.4 ± 6.22 | 29.4 ± 6.18 | 22.1 ± 5.09 | 23.1 ± 7.03 | 0.691 | 0.019 | 0.991 |
| Peak isometric tetanic force (mN) | 220 ± 40.1 | 221 ± 17.1 | 202 ± 38.3 | 192 ± 46.9 | 0.641 | 0.172 | 0.763 |
| Active stiffness (N/m) | 421 ± 91.3 | 448±103 | 391 ±108 | 370 ±102 | 0.942 | 0.197 | 0.563 |
| Passive stiffness (N/m) | 13.0 ± 1.77 | 13.3 ± 0.97 | 15.3 ± 2.43 | 15.4 ± 1.73 | 0.841 | 0.008 | 0.907 |
Data are mean ± SD.