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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Am J Cardiol. 2018 Nov 6;123(3):466–473. doi: 10.1016/j.amjcard.2018.10.027

Table 2:

Body Composition, Spirometry & Hemoglobin data by Fibrosis stage.

Anthropometries Overall Stage 0 Stage 1 Stage 2 Stage 3 P-value
Body Mass Index (kg/m2) 34.0 31.4 34.0 34.4 36.1 0.58
(31.1–38.8) (27.6–39.2) (31.1–45.1) (28.8–43.0) (31.1–38.0)

Body Weight (kg) 91.9 77.3 94.4 90.7 98.2 0.33
(80.6–116.9) (70.3–121.4) (81.9–123.1) (82.7–120.2) (84.9–113.7)

Fat Mass (%) 39.1 38.6 44.0 44.5 35.7 0.92
(33.8–45.9) (31.6–44.1) (29.7–47.4) 31.5–47.3) (35.3–43.4)

Fat Free Mass (%) 60.9 61.4 56.0 55.6 64.4 0.89
(54.1–68.0) (55.9–68.4) (52.7–70.3) (52.7–68.5) (56.7–67.6)

Spirometry Parameters

Forced Vital
Capacity (Liters)
3.14 3.48 3.05 3.14 3.31 0.57
(2.82–3.87) (3.10–3.85) (2.58–3.47) (3.10–3.14) (2.35–4.22)

Forced Vital
Capacity (%)
91 97 90 91 91 0.14
(85–98) (92–101) (80–98) (86–91) (83–92)

Forced Expiratory
Volume-1second (Liters)
2.59 2.77 2.48 2.57 2.65 0.61
(2.25–3.07) (2.53–3.16) (2.21–2.82) (2.49–2.57) (1.83–3.19)

Forced Expiratory
Volume-lsecond (%)
94 99 90 95 93 0.25
(86–100) (94–105) (82–106) (86–95) (84–96)

FEV1/FVC ratio 0.80 0.82 0.81 0.79 0.79 0.44
(0.78–0.83) (0.79–0.82) (0.76–0.85) (0.72–0.79) (0.77–0.82)

Maximal Voluntary
Ventilation (Liters/min)
97.8 94.1 99.9 104.1 104.6 0.38
(80.1–123.1) (76.8–111.2) (82.4–121.2) (90.5–141.8) (74.8–127.8)

Maximal Voluntary
Ventilation (%)
93 89 99 108 105 0.37
(84–111) (82–90) (89–113) (88–121) (75–128)

Breathing Reserve (%) 39 34 39 42 46 0.07
(28–49) (12–41) (17–45) (32–56) (32–59)

Oxygen Carrying Capacity of Blood

Hemoglobin (g/dL) 13.9 13.6 14.3 13.0 0.57
(13.3–16.7) (12.7–15.6) (13.6–14.3) (12.4–13.7)

Abbreviations: kg/m2=kilograms per meter squared; %=percent; FVC=forced vital capacity; FEVl=forced expiratory volume in 1-second; g/dL=grams per deciliter.