TABLE 2. Targeting and Treatment Details.
ECG = Electrocardiography, VT = Ventricular Tachycardia, LV = Left ventricle, SBRT = Stereotactic Body Radiotherapy
Targeting data acquired at baseline (n) (%) Magnetic Resonance Imaging Nuclear imaging Electrocardiographic imaging 12-lead ECG |
9 (47.4) 19 (100) 19 (100) 19 (100) |
Non-invasive Programmed Stimulation Median # of induced VT (range) Median Cycle length of induced VT (milliseconds) (range) |
2 (1–5) 360 (230–690) |
Target location (n) * Segments in Left Ventricle Anterior Lateral Inferior Septal Apex LV Summit Segments in Right ventricle |
5 6 6 3 4 2 1 |
Median Target Volume (cc’s) (range) † Gross target volume Internal target volume Planning target volume |
25.4 (6.4–88.6) 31.0 (17.7–128.9) 98.9 (60.9–298.8) |
Immobilization system (n) (%) Vacuum immobilization (Elekta BodyFIX) Abdominal compression (CDR FreedomX) |
3 (15.8) 16 (84.2) |
Stereotactic Body Radiotherapy technique Volumetric modulated arc therapy Fixed-field intensity modulated therapy |
17(89.5) 2 (10.5) |
Linear accelerator Varian TrueBeam Varian Edge |
3 (15.8) 16 (84.2) |
Median Stereotactic Body Radiotherapy beam-on time (min) (range) | 15.3 (5.4–32.3) |
Segments refers to inclusion of a location as part of targeting for SBRT. Multiple patients had targets that involved more than one segment, so total number adds up to greater than 19.
The target is referred to as the gross target volume (GTV). After outlining the GTV, an additional area around the GTV was added to account for internal motion of the GTV caused by breathing and cardiac motion, as assessed by review of the 4D‐CT. This is called the internal target volume (ITV). Finally, an additional safety margin of 5 mm was added to the ITV region for treatment planning to create a planning target volume (PTV), which accounts for any residual uncertainties in patient setup, motion, and delivery.