TABLE I.

Calculated localized surface plasmon enhancement for 2D IR signals based on measurements of the effective transition dipole strength.

	${\left|\mu \right|}^2$ effective (D2)
	Random
Sample	coil	α-helix	Enhancement factor	2D signal enhancement
Cys-ovispirin-1 on 3 nm	0.92	18.8	7.69–78.3	59.1–6140
Au/CaF2, dry
Cys-ovispirin-1 on 3 nm	1.48	2.81	11.7–12.4	137–153
Au/CaF2, hydrated with D2O