Table 2. Genetic association of BLK (rs6993775) and FCGR2A (rs1801274) with KD in KD subgroups.

KD groups	Subgroups	Number	BLK (rs6993775)				FCGR2A (rs1801274)
			RAF*	OR	95% CI	p‡	RAF†	OR	95% CI	p‡
All		1,011	0.794	1.48	1.32–1.66	4.63×10−11	0.799	1.26	1.12–1.42	1.42×10−4
KD type	cKD	912	0.797	1.51	1.34–1.71	4.03×10−11	0.803	1.29	1.14–1.46	7.47×10−5
	iKD	99	0.763	1.23	0.89–1.72	0.211	0.768	1.05	0.75–1.46	0.794
Age (years)	0 to <1	198	0.780	1.37	1.07–1.74	0.0115	0.849	1.77	1.34–2.34	4.68×10−5
	1 to <2	192	0.802	1.56	1.21–2.01	6.07×10−4	0.784	1.15	0.90–1.47	0.277
	2 to <3	196	0.816	1.71	1.32–2.21	4.42×10−5	0.804	1.29	1.00–1.67	0.0458
	3 to <4	170	0.809	1.63	1.24–2.14	4.54×10−4	0.791	1.20	0.92–1.56	0.181
	4 to <5	107	0.804	1.57	1.12–2.21	8.48×10−3	0.808	1.33	0.95–1.88	0.0985
	≥5	144	0.750	1.15	0.88–1.51	0.302	0.747	0.93	0.71–1.22	0.608
Sex§	Male	611	0.790	1.47	1.26–1.71	1.18×10−6	0.808	1.34	1.14–1.58	3.21×10−4
	Female	400	0.800	1.52	1.27–1.83	6.69×10−6	0.786	1.16	0.97–1.38	0.116
CAL	No	799	0.794	1.48	1.30–1.68	3.09×10−9	0.805	1.31	1.15–1.50	6.77×10−5
	Yes	210	0.793	1.47	1.16–1.87	1.55×10−3	0.774	1.08	0.86–1.37	0.507
Family history	No	988	0.793	1.47	1.31–1.66	1.13×10−10	0.798	1.25	1.11–1.41	2.54×10−4
	Yes	18	0.861	2.38	0.93–6.13	0.0634	0.833	1.58	0.66–3.81	0.302
Recurrence	No	952	0.793	1.47	1.31–1.66	2.11×10−10	0.796	1.23	1.09–1.39	7.35×10−4
	Yes	54	0.833	1.92	1.16–3.19	0.0104	0.852	1.82	1.07–3.10	0.0256
IVIG responsiveness	Responder	842	0.811	1.45	1.28–1.64	6.85×10−9	0.801	1.25	1.10–1.42	7.59×10−4
	Non-responder	148	0.790	1.65	1.23–2.21	7.97×10−4	0.798	1.27	0.95–1.70	0.104

BLK = B lymphoid tyrosine kinase; CAL = coronary artery lesion; CI = confidence interval; cKD = complete type of Kawasaki disease; FCGR2A = Fc gamma receptor II a; iKD = incomplete Kawasaki disease; IVIG = intravenous immunoglobulin; KD = Kawasaki disease; OR = odds ratio; RAF = risk allele frequency.

^*The RAF (risk allele: A; non-risk allele: C) of the control was 0.722 for BLK; ^†The RAF (risk allele: A; non-risk allele: G) of the control was 0.760 for FCGR2A; ^‡The p<0.05 was considered significant and is denoted in bold; ^§The RAF and p for sex were calculated according to the sex specified. The RAFs for BLK were 0.719 and 0.725 for the male and female controls, respectively. The RAFs for FCGR2A were 0.758 and 0.761 for the male and female controls, respectively.