Table 3. Genetic association of BLK (rs6993775) and FCGR2A (rs1801274) with KD after excluding iKD and/or patients ≥5 years old.
| Subgroups | Number | BLK (rs6993775) | FCGR2A (rs1801274) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| RAF* | OR | 95% CI | p‡ | RAF† | OR | 95% CI | p‡ | ||
| All KD | 1,011 | 0.794 | 1.48 | 1.32–1.66 | 4.63×10−11 | 0.799 | 1.26 | 1.12–1.42 | 1.42×10−4 |
| KD without iKD | 912 | 0.797 | 1.51 | 1.34–1.71 | 4.03×10−11 | 0.803 | 1.29 | 1.14–1.46 | 7.47×10−5 |
| KD without those >5 years old | 863 | 0.802 | 1.56 | 1.37–1.77 | 6.90×10−12 | 0.808 | 1.33 | 1.17–1.51 | 1.52×10−5 |
| KD without those with iKD and ≥5 years old | 789 | 0.805 | 1.58 | 1.39–1.81 | 7.57×10−12 | 0.812 | 1.37 | 1.20–1.57 | 4.66×10−6 |
BLK = B lymphoid tyrosine kinase; CI = confidence interval; FCGR2A = Fc gamma receptor II a; iKD = incomplete type of Kawasaki disease; KD = Kawasaki disease; OR = odds ratio; RAF = risk allele frequency.
*The RAF (risk allele: A; non-risk allele: C) of the control was 0.722 for BLK; †The RAF (risk allele: A; non-risk allele: G) of the control was 0.760 for FCGR2A; ‡The p<0.05 was considered significant and is denoted in bold.