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. 2018 Oct 19;49(1):99–108. doi: 10.4070/kcj.2018.0224

Table 4. Sex-stratified genetic association of FCGR2A (rs1801274) with KD in KD subgroups after excluding iKD and ≥5 years old.

KD groups Subgroups Male Female
Number RAF* OR 95% CI p Number RAF* OR 95% CI p
All 474 0.826 1.52 1.26–1.82 4.50×10−6 315 0.792 1.20 0.98–1.46 0.0819
Age (years) 0 to <1 117 0.872 2.17 1.47–3.21 6.69×10−5 66 0.795 1.22 0.80–1.87 0.358
1 to <2 102 0.784 1.16 0.83–1.64 0.388 73 0.801 1.27 0.84–1.91 0.258
2 to <3 111 0.826 1.50 1.05–2.14 0.0238 69 0.790 1.18 0.78–1.79 0.432
3 to <4 88 0.826 1.49 1.01–2.22 0.0447 66 0.758 0.98 0.66–1.47 0.928
4 to <5 56 0.812 1.39 0.86–2.24 0.182 41 0.829 1.53 0.86–2.72 0.150

CI = confidence interval; FCGR2A = Fc gamma receptor II a; iKD = incomplete type of Kawasaki disease; KD = Kawasaki disease; OR = odds ratio; RAF = risk allele frequency.

*The RAFs (risk allele: A; non-risk allele: G) for FCGR2A were 0.758 and 0.761 for the male and female controls, respectively; The p<0.05 was considered significant and is denoted in bold.