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. 2019 Jan 8;8:662. doi: 10.3389/fonc.2018.00662

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Copyright © 2019 Sheng, Pridham, Sheng, Lamouille and Varghese.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of RNAi screen results from Project Achilles. RNAi screen results were retrieved from Project Achilles. Candidate genes were selected based on the following criteria: (1) Genes are targeted by two or more different shRNAs; (2) The fold changes of shRNA loss (log2) are lower than −3; (3) The average fold changes of shRNA loss (log2) are lower than −4. Ten candidates were selected. The fold changes of shRNA loss (log2) in each GBM cell lines are shown in (A) and the average fold changes of shRNA loss are shown in (B). Red lines indicate cut-off numbers ^*P < 0.05.