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. 2019 Jan 8;9:1428. doi: 10.3389/fphar.2018.01428

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Copyright © 2019 Xu, Xu, Jeong, Qian, Wu, Xia and Kong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Role of Nrf2 in NAFLD. Multiple studies have shown that several pathways could activate Nrf2 and inhibit NAFLD and NASH including scutellarin-PPARγ/PGC1α-Nrf2-HO-1/NQO1/GST pathway; green tea extract and ezetimibe activated Nrf2 pathway; osteocalcin activated Nrf2 and subsequently inhibited JNK pathway.