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. 2019 Jan 8;9:1539. doi: 10.3389/fphar.2018.01539

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Copyright © 2019 Fu, Xi, Wang, Zhai, Wang, Gong, Xu, Yang, Qiu, Wang, Lu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of CHB-II-F on body weight, tumor weight and tumor volume of the chemotherapy-treated H₂₂ hepatocellular carcinoma mouse model. (A) Tumor volume (mm³) on 7^th day; (B) Tumor volume (mm³) on 14^th day; (C) Body weight change (g); (D) Weight of tumor (g). Data were presented as the mean ± SD from 6 to 11 mice. Statistical analysis: ^∗P < 0.05, ^∗∗P < 0.01 compared with the saline group. No statistically significant differences were found when compared with the 5-FU group or between YZXJC and CHB-II-F groups (P > 0.05).