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. 2019 Jan 8;9:1539. doi: 10.3389/fphar.2018.01539

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Copyright © 2019 Fu, Xi, Wang, Zhai, Wang, Gong, Xu, Yang, Qiu, Wang, Lu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of CHB-II-F on ultramicro-pathological changes and apoptosis in the chemotherapy-treated H₂₂ hepatocellular carcinoma mouse model. Sections were stained with uranium acetate and lead citrate and viewed under 6000x magnification by transmission electron microscope. (A) Saline treated control (Negative control); (B) 5-FU treated control (20 mg/kg); (C) CHB-II-F (16.25 g/kg); (D) CHB-II-F (32.5 g/kg); (E) CHB-II-F (65 g/kg); (F) Yangzheng Xiaoji Capsule treated control (0.78 g/kg).