Table 3.
Core clinical features obtained from ASAS
ASAS domains | AS (n = 80) | HFA (n = 70) | Differences AS-HFA (95% CI) | Raw p value | Adjusted p value | ||
---|---|---|---|---|---|---|---|
n | % | n | % | ||||
Social emotional abilities | |||||||
Unawareness of the unwritten rules of social play | 48 | 60.0 | 48 | 68.6 | − 8.5% (− 25.2 to 8%) | 0.309 | 0.997 |
Avoid social contact | 29 | 36.3 | 35 | 50.0 | − 13.7% (− 30.8 to 3.3%) | 0.1 | 0.781 |
Excessive amount of reassurance | 60 | 75.0 | 59 | 84.3 | − 9.3% (− 23.4 to 4.8%) | 0.225 | 0.972 |
Not interested in competitive sports and activities | 28 | 35.0 | 30 | 42.9 | − 7.9% (− 24.8 to 9.1%) | 0.401 | 1 |
Communication skills | |||||||
Literal interpretation of comments | 23 | 28.8 | 35 | 50.0 | − 19% (− 35.9 to − 2.1%) | 0.0114 | 0.0431 |
Unusual tone of voice | 57 | 71.3 | 47 | 67.1 | 4.2% (− 12.1 to 20.5%) | 0.5995 | 1 |
Uninterested in other side of the conversation | 56 | 70.0 | 43 | 61.4 | 9.1% (− 7.5 to 25.7%) | 0.3024 | 0.996 |
Less eye contact when in a conversation | 40 | 50.0 | 42 | 60.0 | − 11.2% (− 28.6 to 6.2%) | 0.2516 | 0.988 |
Over-precise or pedantic speech | 45 | 56.3 | 21 | 30.0 | 32.2% (3.6–38.9%) | 0.0017 | 0.0112 |
Cognitive skills | |||||||
Exceptional long-term memory for events/facts | 58 | 72.5 | 37 | 52.9 | 10.5% (− 6.9 to 28%) | 0.0172 | 0.0511 |
Specific interests | |||||||
Fascinated by a particular topic | 63 | 78.8 | 47 | 67.1 | 12.9% (− 3.4 to 29.2%) | 0.1389 | 0.876 |
To be unduly upset by changes in routine | 53 | 66.3 | 49 | 70.0 | − 3.2% (− 20.4 to 14.1%) | 0.7261 | 1 |
To develop routines/rituals | 40 | 50.0 | 38 | 54.3 | − 6.3% (− 24.7 to 12%) | 0.6263 | 1 |
Movement skills | |||||||
Poor motor coordination | 50 | 62.5 | 44 | 62.9 | − 5.2% (− 22.4 to 12.1%) | 1 | 1 |
Other characteristics | |||||||
Unusual fear/distress due to light touch on skin or scalp | 25 | 31.3 | 25 | 35.7 | − 4.7% (− 21.8 to 12.3%) | 0.605 | 1 |
Unusual fear/distress due to unexpected noises | 45 | 56.3 | 32 | 45.7 | 5.7% (− 12.9 to 24.5%) | 0.2518 | 0.99 |
A tendency to flap or rock when excited/distressed | 38 | 47.5 | 39 | 55.7 | − 6.8% (− 24.8 to 11.3%) | 0.3308 | 1 |
Late in acquiring speech | 26 | 32.5 | 39 | 55.7 | − 23.2% (− 40.1 to − 6.4%) | 0.0051 | 0.0234 |
AS Asperger syndrome, HFA high functioning autism, CI confidence interval