Table 1.
Mean (SD) demographic characteristics of patients and controls
| HC | naPPA | lvPPA | svPPA | P | |
|---|---|---|---|---|---|
| n | 31 | 15 | 23 | 21 | |
| Age, y | 69.29 (7.90) | 69.67 (9.20) | 65.91 (9.83) | 64.48 (7.71) | 0.14 |
| Sex = Male (%) | 11 (35.5) | 6 (40.0) | 7 (30.4) | 10 (47.6) | 0.68 |
| Education, y | 15.97 (2.58) | 14.80 (3.12) | 15.35 (3.19) | 15.10 (2.81) | 0.56 |
| Disease duration, y | NA | 2.60 (1.12) | 4.00 (2.00) | 4.05 (2.04) | 0.04 |
| MMSE total (0‐30), n = 85 | 29.00 (1.07) | 24.73 (5.24) | 23.05 (5.72) | 23.05 (6.11) | <0.001a |
| PBAC Naming (0‐6), n = 37 | 5.50 (0.71) | 5.78 (0.67) | 4.00 (1.83) | 1.23 (1.48) | <0.001 |
| F letter fluency, n = 41 | 17.75 (8.10) | 6.33 (3.04) | 6.36 (5.40) | 8.21 (3.96) | 0.001 |
| Digit span forward, n = 69 | 7.00 (1.37) | 5.61 (1.30) | 4.45 (1.54) | 6.06 (1.89) | <0.001 |
| Digit span backward, n = 74 | 5.65 (1.31) | 2.64 (1.11) | 2.91 (1.08) | 3.78 (1.70) | <0.001 |
| Category fluencyd, n = 54 | 19.67 (6.48) | 10.11 (5.09) | 9.85 (5.94) | 5.36 (4.67) | <0.001 |
| Total speech timeb (sec) | 49.66 (18.23) | 33.78 (18.53) | 38.54 (15.02) | 36.42 (13.85) | 0.006 |
| Total word countc | 166.32 (63.90) | 65.80 (37.06) | 114.13 (56.80) | 134.05 (55.99) | <0.001 |
| Speech rate, wpm | 140.06 (36.74) | 61.00 (24.85) | 88.17 (36.09) | 113.95 (40.76) | <0.001 |
| MLU (words) | 10.57 (1.98) | 6.74 (2.38) | 8.46 (2.45) | 8.61 (2.75) | <0.001 |
| DC/utterancee | 0.37 (0.23) | 0.05 (0.09) | 0.21 (0.21) | 0.32 (0.27) | <0.001 |
| WFS/utterance | 0.91 (0.11) | 0.72 (0.32) | 0.71 (0.25) | 0.78 (0.19) | 0.003 |
wpm, words per minute; MLU, mean length of utterance; DC, dependent clauses; WFS, well‐formed sentences; PBAC, Philadelphia Brief Assessment of Cognition.
a
MMSE total score did not differ between patient groups.
b
This refers to the sum of all subject's speech segment durations, including verbal and nonverbal vocalizations, all available for pitch‐tracking.
c
This manual word count includes only verbal vocalizations that were comprehensible enough for transcription.
d
Category = animals
e
Data refer to the average number of clauses per utterance.