Table 2.

The detection of miRNA ratios as potential biomarkers for diagnosis of early stage breast cancer (Cancer vs. Benign).

Ratio	Cancer	Benign	Fold Change	Regulation	p-value	FDR	AUC
miRNA30a/miRNA382	3.149	0.696	5.477	Up	2.1102E-05	0.0003	0.740
miRNA192/miRNA382	1.288	–1.073	5.138	Up	2.6838E-06	9.3932E-05	0.776
miRNA324/miRNA382	–0.984	–3.301	4.985	Up	2.3742E-06	9.3932E-05	0.784
miRNA21/miRNA382	4.570	2.296	4.836	Up	1.2653E-05	0.0003	0.736
miRNA1273g/miRNA382	1.712	–0.403	4.332	Up	2.1948E-05	0.0003	0.720
miRNA222/miRNA382	2.617	0.504	4.327	Up	5.7468E-05	0.0007	0.731
miRNA451/miRNA382	7.717	5.800	3.777	Up	0.0035	0.0192	0.641
miRNA152/miRNA382	–0.257	–2.139	3.684	Up	0.0001	0.0012	0.719
miRNA22/miRNA382	2.993	1.511	2.794	Up	0.006	0.0243	0.642
miRNA30e/miRNA382	1.616	0.144	2.773	Up	0.0038	0.0196	0.672
miRNA574/miRNA382	2.195	0.940	2.387	Up	0.0039	0.0196	0.606
miRNA192/miRNA574	–0.907	–2.013	2.152	Up	0.0034	0.0192	0.688
miRNA192/miRNA221	–1.299	–2.368	2.097	Up	0.0051	0.0233	0.658
miRNA21/miRNA574	2.375	1.357	2.026	Up	0.0051	0.0233	0.671
miRNA30a/miRNA30e	1.534	0.552	1.975	Up	2.3208E-06	9.3932E-05	0.801
miRNA21/miRNA221	1.983	1.001	1.974	Up	0.0003	0.0026	0.732
miRNA192/miRNA30e	–0.328	–1.217	1.853	Up	0.0113	0.0397	0.650
miRNA192/miRNA22	–1.705	–2.584	1.839	Up	0.0125	0.0422	0.648
miRNA21/miRNA30e	2.954	2.152	1.744	Up	0.0032	0.0192	0.684
miRNA21/miRNA22	1.577	0.786	1.731	Up	0.0011	0.0086	0.741
miRNA22/miRNA222	0.376	1.007	–1.549	Down	0.0083	0.0313	0.652
miRNA221/miRNA222	–0.030	0.791	–1.767	Down	0.0021	0.0139	0.698
miRNA574/miRNA1273g	0.483	1.343	–1.815	Down	0.0017	0.0117	0.703
miRNA22/miRNA30a	–0.156	0.815	–1.960	Down	1.7733E-05	0.0003	0.793
miRNA221/miRNA324	3.571	4.596	–2.035	Down	0.0055	0.0233	0.669
miRNA574/miRNA324	3.179	4.241	–2.088	Down	0.0114	0.0397	0.657
miRNA221/miRNA30a	–0.562	0.599	–2.236	Down	3.3603E-05	0.0004	0.763
miRNA574/miRNA30a	–0.955	0.244	–2.294	Down	0.0056	0.0233	0.686

RT-qPCR tested miRNAs are in bold.