Table 1.
Different forms of BAK1-mediated PCD in plants.
| PCD type | Trigger of PCD | Receptor | Perturbation of BAK1 function | PCD phenotype | Possible Regulation | Reference |
|---|---|---|---|---|---|---|
| PCD by disruption of BAK1 and related proteins | bkk1/serk4 | bak1 | Spontaneous cell death | Phosphorylation; Glycosylation | He et al., 2007; Kemmerling et al., 2007; Jeong et al., 2010; de Oliveira et al., 2016 | |
| BAK1 OE | BAK1 over-expression | Spontaneous cell death, BRI1 OE suppress this cell death | Domnguez-Ferreras et al., 2015; Kim et al., 2017 | |||
| SOBIR1 OE | NA | Spontaneous cell death | Phosphorylation | Gao et al., 2009; Liebrand et al., 2014 | ||
| bir1 | bak1 | Spontaneous cell death dependent on SOBIR1 | Phosphorylation | Gao et al., 2009 | ||
| bir2 | bak1 | enhanced HP upon pathogen | Phosphorylation | Halter et al., 2014; Liu et al., 2016; Imkampe et al., 2017 | ||
| bir3 | bak1 | Enhanced HR | Phosphorylation | Halter et al., 2014; Imkampe et al., 2017 | ||
| bon1 | NA | Spontaneous cell death | Phosphorylation | Wang et al., 2011; Kim et al., 2017; | ||
| CRK28 OE | NbSerk3 silencing | Suppressed HR | Glycosylation | Yadeta et al., 2016, 2017 | ||
| bir1pad4-1 | sobir7-1/bak1 | Suppressed HR | Liu et al., 2016; Wu et al., 2018 | |||
| bPCD by PAMPs | SCFE1 (Sclerotnia) | RLP30-SOBIR1 | bak1 | suppressed HR | Zhang et al., 2013 | |
| NLP (bacteria, fungi, oomycete) | RLP23-SOBIR1-BAK1 | bak1 | suppressed HR | Albert et al., 2015 | ||
| INF1 (Phytophthora infestans) | Sl ELR-SOBIR1 | bak1 | Suppressed HR | Heese et al., 2007; Chaparro-Garcia et al., 2011; Domazakis et al., 2018 | ||
| BcXYG1 (Botrytis) | BAK1-SOBIR1 | bak1 | Suppressed HR | Zhu et al., 2017 | ||
| BcScp1 (Botrytis) | bak1 | Suppressed HR | Dagvadorj et al., 2017 | |||
| Eix (fungal) | LeEix1/2 (LRR-RLP) | BAK1 silencing | Suppressed HR | Bar et al., 2010 | ||
| Pst SCR1 (Puccinia stratiform) | bak1 | Suppressed HR | Dagvadorj et al., 2017 | |||
| pep2 | PEPR | bak1 | Enhanced HR | Yamada et al., 2016 | ||
| bPCD upon pathogen | Hpa | bak1 | Enhanced HR | Heese et al., 2007 | ||
| Alternaria | bir2 | Enhanced HR | Halter et al., 2014 | |||
| bPCD by effector | Aphid | Mi-1 (NLR) | bak1 | Suppressed HR | Peng et al., 2016 | |
| FolAvr1 (Fusarium) | I (LRR LRP) | bak1 | Suppressed HR | Catanzariti et al., 2017 | ||
| Avr4/9 (Cladosporium) | Cf-4, Cf-9 | bak1 | Suppressed HR | Endocytosis | Postma et al., 2016 | |
| dPCD | TDIF | PXY | bak1 | Treachery element PCD | Ma et al., 2016; Zhang et al., 2016 | |
| TPD1 | EMS1 | serk1/2 | Tapetal PCD | Li Z. et al., 2017 | ||
| IDA | HSA/HSL2 | serk1/2/3 | PCD in abscission zone | Meng et al., 2016 | ||