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Effect of combined administration of DMPX and antidepressants in the FST (a) and TST (b) in mice. Antidepressants and saline were administered i.p. 60 min, whereas DMPX i.p. 30 min before the test. Each experimental group consisted of 10 animals. The data are presented as the means ± SEM. ***p < 0.001, ****p < 0.0001 versus respective antidepressant-treated group; ^^p < 0.01, ^^^^p < 0.0001 versus DMPX-treated group (two-way ANOVA followed by Bonferroni’s post hoc test)
