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. 2019 Jan 14;9:100. doi: 10.1038/s41598-018-36614-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparative analysis of the in vivo and in vitro flow fields. Streamlines color coded with velocity magnitudes at the peak systolic phase in vitro (top left) and in vivo (bottom left) (higher velocity magnitudes occur in the proximity of the RVOT, whereas the velocity magnitudes are comparatively lower at the RV subtricuspid region and the apex). Dashed lines represent the investigation domain where the statistical analysis has been performed. The linear regression analysis between velocity magnitude normalized by peak velocity magnitude in vivo and in vitro (top right) and Bland-Altman analysis between velocity magnitude normalized by peak velocity magnitude in vivo and in vitro (bottom right). Filled blue circles represent a different time-point in the cardiac cycle.