Table 3.
Author, year, country | Study type and population | FGR definition | Determinant(s) | Outcome | Results |
---|---|---|---|---|---|
Egbor et al., 2006United Kingdom | Prospective A: 17 FGR B: 16 PE-FGR C: 16 controls |
- Clinical evidence of suboptimal growth - Ultra sonographic evidence of deviation from appropriate growth percentile - BW < p10 |
PV, PW | FGR | FGR was associated with a significant reduction in PV and PW |
Mayhew et al., 2007, United Kingdom | Prospective A: 5 FGR B: 5 PE-FGR C: 9 controls |
- Deficient fetal growth on ultrasound scans - IBR < p10 |
PSA | Morphometry determinant in the different groups | FGR (with or without PE) was associated with a reduced PSA |
Almasry and Elfayomy, 2012, Saudi Arabia | Case-control A: 50 FGR B: 25 controls | EFW < p10 icw two criteria: - Abnormal UmA Doppler - Oligohydramnios; AFI < 5 - Asymmetric growth; HC/AC ratio |
PD, PW, “placenta co-efficient” (PW/BW). | FGR | Significant reduction in PD and PW in FGR group as compared with controls. Placental coefficient greater in FGR group. |
AC, abdominal circumference; BW, birth weight; EFW, estimated fetal weight; FGR, fetal growth restriction; HC, head circumference; IBR, individualized birth weight ratio (is calculated using factors including fetal gender, GA, parity, ethnic origin and maternal age, height and booking weight); icw, in combination with; PE, preeclampsia; PD, placental diameter; PSA, macroscopic placental surface area; PV, placental volume; PW, placental weight; UmA, umbilical artery.