Table 2. Genotypes distribution of MTR A2756G polymorphism in cases and controls.
Reference | Sample size | Case group | Control group | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | AA | AG | GG | A | G | AA | AG | GG | A | G | PHWE | |
de Jonge et al. [23] | 245 | 489 | 162 | 74 | 9 | 398 | 92 | 340 | 137 | 12 | 817 | 161 | 0.68 |
Gast et al. [24] | 446 | 547 | 280 | 153 | 13 | 713 | 179 | 375 | 151 | 21 | 901 | 193 | 0.24 |
Kamel et al. [25] | 87 | 306 | 55 | 29 | 3 | 139 | 35 | 194 | 97 | 15 | 485 | 127 | 0.53 |
Lautner-Csorba et al. [26] | 543 | 529 | 344 | 175 | 24 | 863 | 223 | 341 | 163 | 25 | 845 | 213 | 0.34 |
Lightfoot et al. [27] | 870 | 759 | 531 | 288 | 51 | 1350 | 390 | 510 | 223 | 26 | 1243 | 275 | 0.79 |
Metayer et al. [28] | 376 | 447 | 237 | 123 | 16 | 597 | 155 | 292 | 137 | 18 | 721 | 173 | 0.70 |
Milne et al. [29] | 391 | 514 | 251 | 130 | 10 | 632 | 150 | 337 | 158 | 19 | 832 | 196 | 0.93 |
Petra et al. [30] | 68 | 258 | 51 | 16 | 1 | 118 | 18 | 161 | 82 | 15 | 404 | 112 | 0.30 |
Rahimi et al. [31] | 73 | 128 | 42 | 26 | 5 | 110 | 36 | 75 | 47 | 6 | 197 | 59 | 0.69 |
Nikbakht et al. [32] | 125 | 100 | 74 | 44 | 7 | 192 | 58 | 58 | 35 | 7 | 151 | 49 | 0.59 |
Abbreviations: HWE, Hardy–Weinberg equilibrium; MTR, methionine synthase.