Figure 6. PCs are the main substrates of CANX‐FAM134B complex.

• A, B
  Volcano plot comparing protein fold changes between WT versus Fam134b ^−/− (A) and WT versus Canx ^−/− MEFs (B). Significantly regulated proteins are labelled in red (log₂ fold change > 1, −log₁₀ P > 1.3). Red dots with blue ring indicate collagen 1 peptides. Graphs represent statistics from three separate experiments for each genotype.
• C
  Left: Venn diagrams represent the number of identified peptides significantly enriched in Fam134b ^−/− and Canx ^−/− MEFs. Right: List of peptides upregulated in both Fam134b ^−/− and Canx ^−/− MEFs.