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. 2019 Jan 8;6:645. doi: 10.3389/fchem.2018.00645

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Copyright © 2019 Yorulmaz Avsar, Kyropoulou, Di Leone, Schoenenberger, Meier and Palivan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Concept of a pH-responsive surface. Polymer nanocompartments containing a pH-sensitive dye are immobilized on a glass surface. Signaling consists of either an increase or quenching of fluorescence. (B) Nanocompartment pH response in solution. Decrease in fluorescent signal upon addition of lactic acid (measured pH range 8 – 6) (right). Increase in fluorescence upon addition of ethylenediamine, a biogenic amine (measured pH range 6 – 8) (n = 3) (left). Reproduced from Craciun et al. (2018) with permission of Copyright © 2018 Wiley-VHCA AG, Zurich, Switzerland.