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. 2019 Jan 8;6:645. doi: 10.3389/fchem.2018.00645

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Copyright © 2019 Yorulmaz Avsar, Kyropoulou, Di Leone, Schoenenberger, Meier and Palivan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Polymersome attachment on the alkyne modified PAN membrane surface. (A) Cryo-SEM images of membrane supported immobilized polymersomes after extensive washing. Top, Amine-terminated ABA polymersomes on hydrolyzed PAN membranes. The membrane pores are visible. Bottom, Azide-terminated ABA polymersomes on alkyne-functionalized PAN. A continuous layer of collapsed polymersomes can be observed. (B) Schematic representation of polymersome-clicking on the alkyne modified PAN membrane surface. (C) left, AFM of a PAN membrane covered with polymersomes immobilized by CuAAC on alkyne-functionalized PAN. A partially covered area was selected to determine the layer thickness and the shape of assembled polymersomes. AFM cross section (green line) is shown on the right. Reproduced (with adaptations) from Rein et al. (2016) with permission of Copyright © 2016 Wiley Periodicals, Inc.