Table 4.

Crude hazard ratios (95% CI) shown for ages 70, 80 and 90 years in the patient groups according to a Poisson regression model

Current age (year)	Prostate cancer without ADT vs. no prostate cancer	Prostate cancer withADT vs. no prostate cancer	Prostate cancer with ADT vs. prostate cancer without ADT
Any fracture	Interaction term p < 0.001	Interaction term p = 0.12	Interaction term p < 0.001
70	0.63 (0.53, 0.75)*	1.66 (1.33, 2.07)*	2.63 (1.99, 3.48)*
80	0.83 (0.75, 0.93)*	1.49 (1.31, 1.71)*	1.79 (1.50, 2.13)*
90	1.11 (0.97, 1.26)	1.35 (1.16, 1.56)*	1.22 (1.00, 1.48)*
Hip fracture	Interaction term p < 0.001	Interaction term p = 0.006	Interaction term p < 0.001
70	0.55 (0.41, 0.74)*	2.15 (1.53, 3.02)*	3.89 (2.51, 6.02)*
80	0.80 (0.66, 0.96)*	1.63 (1.33, 1.99)*	2.04 (1.56, 2.67)*
90	1.15 (0.95, 1.39)	1.23 (0.99, 1.53)	1.07 (0.81, 1.42)
MOF	Interaction term p < 0.001	Interaction term p = 0.005	Interaction term p < 0.001
70	0.70 (0.56, 0.88)*	2.09 (1.58, 2.77)*	2.99 (2.09, 4.26)*
80	0.93 (0.80, 1.08)	1.64 (1.39, 1.95)*	1.76 (1.41, 2.20)*
90	1.24 (1.05, 1.46)*	1.29 (1.07, 1.56)*	1.04 (0.82, 1.33)
Non-skeletal fall injury	Interaction term p < 0.001	Interaction term p > 0.30	Interaction term p = 0.12
70	0.71 (0.58, 0.86)*	0.97 (0.72, 1.31)	1.38 (0.98, 1.95)
80	0.88 (0.77, 1.01)	1.03 (0.86, 1.24)	1.17 (0.94, 1.45)
90	1.11 (0.94, 1.30)	1.10 (0.90, 1.33)	0.99 (0.78, 1.26)

*p < 0.001. An extension of Poisson regression models was used to study the association between potential predictors and the future risk of fracture. The observation period of each participant was divided into intervals of 1 month. One fracture per person and time to the first fracture were counted, and time at risk was censored at the time of first fracture, loss to follow-up, death or end of follow-up. Since the current time, since baseline and current age are used in the model i.e. the age at each time of follow up, not the age at baseline, the model is taking care of competing risk. The association between predictive factors and risk of fracture is described as a hazard ratio (HR) at baseline of the study, per 1 unit change in predictor together with 95% confidence intervals (CI)