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. 2018 Nov 23;34(2):309–317. doi: 10.1007/s00384-018-3198-0

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — a Patients with high sICAM-1 concentrations present with a worse overall (p < 0.001) and cancer-related survival (p < 0.001) compared to patients with low sICAM-1 concentrations. b Combination of CEA and sICAM-1 serum concentrations identifies four significant (p < 0.001) different risk groups in CRC patients (n = 297). c Relative proportion in percent of UICC I–IV stages in patients with low and high sICAM-1 concentrations (left). Relative proportion in percent of UICC I–IV stages of combined sICAM-1/CEA score (right)