. 2018 Nov 23;34(2):309–317. doi: 10.1007/s00384-018-3198-0

Table 5.

High soluble ICAM-1 concentrations identify a high-risk subgroup within colorectal carcinoma patients presenting with either normal or elevated CEA concentrations

		n	5-year survival/95% CI	p value
Overall survival				6.037E−12
Score 1	CEA normal, sICAM-1^low	151	85.4/79.7–91.1	0.025*
Score 2	CEA normal, sICAM-1^high	48	72.6/59.9–85.3	0.093**
Score 3	CEA elevated, sICAM-1^low	57	48.7/35.6–61.8	0.017***
Score 4	CEA elevated, sICAM-1^high	41	29.1/15.2–43.0
Cancer-related survival				3.382E−15
Score 1	CEA normal, sICAM-1^low	151	92.2/87.9–96.5	0.155*
Score 2	CEA normal, sICAM-1^high	48	86.0/75.6–96.4	0.009**
Score 3	CEA elevated, sICAM-1^low	57	59.1/45.4–72.8	0.028***
Score 4	CEA elevated, sICAM-1^high	41	42.4/25.9–58.9

Soluble ICAM-1 soluble intercellular adhesion molecule-1, CEA carcinoembryonic antigen

*Score 1 vs. score 2

**Score 2 vs. score 3

***Score 3 vs. score 4