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. 2015 Sep 15;20(9):16758–16769. doi: 10.3390/molecules200916758

Figure 4.

Figure 4

(A) Effect of the pretreatment with CORM 3 (3.0 mg/kg i.p.) on the antiallodynic effect of H. procumbens (300 mg/kg i.p.) in carrageenan-injected rats (2%/0.1 mL/rat). Mechanical thresholds were measured with von Frey’s filaments. Results are expressed in grams (g) and represent the means ± SEM from 8 to 10 rats. # p < 0.05 vs. saline treated-rats; § p < 0.05 vs. carrageenan injected-rats; (B) Effect of the pretreatment with CORM 3 (3.0 mg/kg i.p.) on the antihyperalgesic effect of H. procumbens (300 mg/kg i.p.) in carrageenan-injected rats (2%/0.1 mL/rat). Thermal thresholds were measured with Plantar test. Results are expressed in seconds (s) and represent the means ± SEM from 8 to 10 rats. # p < 0.05 vs. saline treated-rats; § p < 0.05 vs. carrageenan injected-rats.