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. 2015 Nov 2;20(11):19764–19774. doi: 10.3390/molecules201119656

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Response surface plots and contour plots show the effect of extraction variables on tyrosinase inhibition (A–C) and antioxidant activity (D–F). Three variables are EtOAc concentration (X₁), extraction time (X₂), and extraction temperature (X₃).

Response surface plots and contour plots show the effect of extraction variables on tyrosinase inhibition (A–C) and antioxidant activity (D–F). Three variables are EtOAc concentration (X₁), extraction time (X₂), and extraction temperature (X₃).