Table 3.
Aptamer | EC50 (nM) a | HCV-CRE194:NS5BΔ21 Complex (%) b |
---|---|---|
P6-89 | 14.59 ± 1.11 | 5.09 ± 2.04 |
P6-96 | 38.68 ± 5.63 | 0.00 ± 4.15 |
P6-103 | 8.57 ± 0.58 | 11.98 ± 1.46 |
P7-49 | n.d. | 75.37 ± 3.05 |
a EC50 values were derived from the equation y = 100/(1 + 10(LogEC50−x)); b Data correspond to the highest concentration of inhibitor tested. Values are the mean of three independent assays ± the standard deviation (SD). n.d., non-determined.