Table 2.
Antifungal activity of some compounds against eight pathogens *.
| Compd. | IC50 (μg/mL) (CI 95%) ** | |||||||
|---|---|---|---|---|---|---|---|---|
| V. m. | B. b. | S. f. | G. c. | A. a. | S. s. | A. s. | C. s. | |
| II-1 | 32.0800 (26.1510–39.3533) |
31.2568 (23.7127–41.2012) |
14.6778 (10.7872–19.9716) |
36.3526 (29.1302–45.3658) |
42.2537 (33.7577–52.8879) |
7.2482 (2.9912–17.5637) |
30.1335 (23.3387–38.9065) |
22.7788 (16.0894–32.2493) |
| II-4 | 27.8016 (22.1312–34.9249) |
24.8446 (18.2585–33.8063) |
10.6665 (7.6148–14.9412) |
16.7764 (11.7587–23.9352) |
31.4258 (24.6239–40.1066) |
4.2858 (1.6648–11.0334) |
14.0938 (9.1043–21.8178) |
10.4051 (12.9130–24.7109) |
| II-5 | 20.1058 (14.8666–27.1914) |
19.8375 (14.7821–26.6217) |
2.0791 (1.3098–3.3003) |
11.2505 (6.9283–18.2691) |
18.1002 (13.1268–24.9579) |
3.4556 (1.6958–7.0418) |
10.4753 (6.7490–16.2590) |
10.4051 (6.4109–16.8880) |
| II-8 | 11.3756 (7.2790–17.7778) |
13.6528 (9.8721–18.8814) |
0.8805 (0.4243–1.8275) |
7.7364 (3.8335–15.6128) |
13.8916 (9.3377–20.6664) |
0.9698 (0.4790–1.9633) |
5.1863 (2.5133–10.7020) |
7.5908 (4.4564–12.9298) |
| II-11 | 17.0896 (11.9965–23.3450) |
17.0640 (12.6223–23.0689) |
2.3717 (1.4367–3.9152) |
9.1071 (5.1797–16.0125) |
22.1465 (16.7792–29.2308) |
2.1783 (0.9142–5.1904) |
12.1081 (7.9591–18.4200) |
12.9298 (8.9552–18.6685) |
| II-14 | 47.7810 (39.0992–58.39.4) |
37.3895 (28.8394–48.4746) |
21.9666 (16.3757–29.4664) |
57.0963 (45.2452–72.0517) |
49.1546 (39.1730–61.6795) |
9.6192 (4.2886–21.5754) |
34.8290 (27.5093–44.0964) |
29.8409 (16.0894–32.2493) |
| Norcantharidin | 17.1862 (9.2272–32.0104) |
141.8133 (61.1287–328.9946) |
17.1673 (10.0952–29.1937) |
465.1719 (86.5242–2500.8598) |
394.9566 (73.9654–2108.9689) |
54.5899 (32.0147–93.0839) |
594.2606 (211.1064–1672.8327) |
NA *** |
| Cantharidin | 21.9320 (13.3453–36.0436) |
147.4225 (46.8714–463.6810) |
2.2175 (0.6116–12.0751) |
155.0286 (76.7546–313.1261) |
14.0428 (5.6729–34.7622) |
14.0622 (8.0013–24.7142) |
28.5223 (18.6015–43.7340) |
18.3900 (8.3854–40.3309) |
| TBZ | 0.5191 (0.0218–12.3413) |
15.5378 (8.8501–27.2793) |
3.1998 (1.2133–8.4391) |
22.3806 (10.4428–47.9653) |
47.8696 21.2217–107.9790 |
1.2947 (0.6661–2.5165) |
1268.5889 (110.6555–1453.4930) |
621.7874 60.1464–6427.9804 |
* V. m.: Valsa mali, B. b.: Botryosphaeria berengeriana, S. f.: Sclerotinia fructigena, G. c.: Glomerella cingulate, A. a.: Alternaria alternate, S. s.: Sclerotinia sclerotiorum, A. s.: Alternaria solani, C. s.: Cochliobolus sativum. ** CI 95%: Confidence interval at 95% probability (µg/mL). *** NA: Not Available.