Table 2.

Anti-inflammatory effect.

Compd. No.	Dose [mg/kg]	% Protection against Edema	% Inhibition of Plasma PGE2
5a	2.5	31.76 ± 0.66	72.19 ± 0.45
	5	40.05 ± 0.77	73.78 ± 0.43
5b	2.5	69.10 ± 0.85	82.65 ± 0.56
	5	71.42 ± 0.96	84.25 ± 0.45
5c	2.5	78.65 ± 0.87	83.59 ± 0.68
	5	88.96 ± 0.78	85.19 ± 0.79
5d	2.5	67.32 ± 0.89	83.13 ± 0.80
	5	70.60 ± 0.90	84.72 ± 0.97
5e	2.5	92.88 ± 0.97	91.73 ± 0.53
	5	97.15 ± 0.86	93.31 ± 0.46
5f	2.5	31.36 ± 0.55	61.28 ± 0.43
	5	33.74 ± 0.64	62.84 ± 0.56
5g	2.5	41.82 ± 0.75	80.82 ± 0.44
	5	44.21 ± 0.66	82.38 ± 0.21
5h	2.5	42.28 ± 0.57	75.49 ± 0.45
	5	54.68 ± 0.75	77.13 ± 0.89
5i	2.5	40.45 ± 0.63	75.96 ± 0.96
	5	42.80 ± 0.54	77.61 ± 0.89
5j	2.5	26.46 ± 0.45	66.45 ± 0.83
	5	28.71 ± 0.56	68.11 ± 0.83
5k	2.5	19.99 ± 0.67	66.93 ± 0.83
	5	22.34 ± 0.78	68.60 ± 0.98
5l	2.5	38.10 ± 0.69	75.01 ± 0.65
	5	40.29 ± 0.77	76.65 ± 0.34
Diclofenac sodium	2.5	69.59 ± 0.44	55.49 ± 0.80
	5	72.19 ± 0.54	70.59 ± 0.80
Valdicoxib	2.5	78.89 ± 0.33	60.09 ± 0.86
	5	87.19 ± 0.23	81.11 ± 0.21

Values were calculated from the mean values of data from three separate experiments; All results are significant different from control values at p ≤ 0.005; All results are significant different from reference standard values at p ≤ 0.005.