Table 2.

Binding constants and thermodynamic parameters of the interaction between compounds 1–4 and BSA at different temperatures.

Compound	T (K)	Kb (L∙mol−1)	∆G° (L∙mol−1)	∆H° (kJ∙mol−1)	∆S° (kJ∙mol−1)	r
1	298	1.438 × 104 ± 1.923	−23.718	52.076	0.2543	0.8464
	303	6.879 × 104 ± 1.217	−28.060	52.076	0.2543	0.8093
	310	3.244 × 104 ± 1.361	−26.771	52.076	0.2543	0.9137
2	298	2.541 × 104 ± 1.246	−25.913	91.697	0.932	0.9652
	303	4.680 × 104 ± 1.134	−27.090	91.697	0.932	0.9813
	310	6.823 × 104 ± 1.208	−28.687	91.697	0.932	0.9435
3	298	5.040 × 104 ± 1.146	−26.827	14.915	0.140	0.9769
	303	5.567 × 104 ± 1.101	−27.527	14.915	0.140	0.9873
	310	6.281 × 104 ± 1.115	−28.474	14.915	0.140	0.9820
4	298	2.341 × 105 ± 1.030	−30.361	−12.221	0.143	0.9961
	303	2.158 × 105 ± 1.022	−30.940	−12.221	0.143	0.9980
	310	1.847 × 105 ± 1.056	−31.254	−12.221	0.143	0.9884