Table 2.
Examples of scoring functions implemented in widely used molecular docking programs.
| Force-Field-Based | Empirical | Knowledge-Based |
|---|---|---|
| DOCK [32] | AutoDock [34] | SMoG [82] |
| AutoDock [34] | GlideScore [37] | DrugScore [62] |
| GoldScore [35] | ChemScore [60] | PMF_Score [83] |
| ICM [46] | X_Score [66] | MotifScore [84] |
| LigandFit [47] | F_Score [73] | RF_Score [85] |
| Molegro Virtual Docker [48] | Fresno [75] | PESD_SVM [86] |
| SYBYL_G-Score [73] | SCORE [76] | PoseScore [87] |
| SYBYL_D-Score [73] | LUDI [77] | |
| MedusaScore [74] | SFCscore [78] | |
| HYDE [79] | ||
| LigScore [80] | ||
| PLP [81] |