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Examples of phytochelators containing a cyclic hydroxamate in the metal binding site and phytochelators used in clinical diagnostics and clinical trials. DIMBOA or 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (35), 8-hydroxyquinoline or quinolin-8-ol (36), silibinin or (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzo-dioxin-6-yl]-2,3-dihydrochromen-4-one (37).
