. 2015 Jul 17;20(7):12992–13004. doi: 10.3390/molecules200712992

Table 3.

Anti-proliferative activity of olive leaf extracts (0–200 µg/mL) on MiaPaCa-2 pancreatic cancer cells. Results are expressed as % viability compared to controls ± standard deviation.

Solvent	Cultivar	Gemcitabine (50 nM)	Concentration of Olive Leaf Extract (µg/mL)
Solvent	Cultivar	Gemcitabine (50 nM)	0 (Controls)	50	100	200
water	Corregiola		100 ^a,i	55.89 ± 3.53 ^b,i	14.59 ± 0.5 ^c,i	0.63 ± 0.29 ^c,i
ethanol	Corregiola		100 ^a,i	121.59 ± 13.7 ^a,ii	4.26 ± 2.6 ^b,ii	0.44 ± 2.08 ^b,i
methanol	Corregiola		100 ^a,i	73.57 ± 9.33 ^b,ii	32.83 ± 10.41 ^c,iii	0.87 ± 0.17 ^d,i
water	Frantoio		100 ^a,i	103.19 ± 27.9 ^a,ii	0.47 ± 0.13 ^b,ii	0.61 ± 0.17 ^b,i
ethanol	Frantoio		100 ^a,i	122.78 ± 21.1 ^a,ii	30.37 ± 4.48 ^b,iii	0.87 ± 0.22 ^c,i
methanol	Frantoio		100 ^a,i	120.26 ± 9.22 ^b,ii	41.13 ± 16.02 ^c,iii	0.98 ± 0.56 ^c,i
	control		100 ^a,i
		47.8 ± 0.1

^a,b,c,d Values in the same row not having the same superscript letter are significantly different from each other. ^i,ii,iii Values in the same column not having the same superscript roman numeral are significantly different from each other. Values are expressed as percentage growth compared to controls with no extracts or gemcitabine. Therefore, the lower the value in response to olive leaf extract (50–200 μg/mL), the greater the anti-proliferative effect. Values greater than 100% represent cell growth greater than controls. Time = 96 h.