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. 2015 Jun 26;20(7):11793–11807. doi: 10.3390/molecules200711793

Figure 2.

Figure 2

Protein sequence alignment of human and flatworm TGRs. Partial sequences from M. vogae (Mv), S. mansoni (Sm, AAK85233.1), E. granulosus (Eg, AAN63052.1) and H. sapiens (Hs, NP_443115.1) TGRs are aligned and N-terminus and C-terminus of the proteins are shown in (a,b), respectively. Conserved domains and mitochondrial targeting signal are represented by boxes above the alignment. Mitochondrial and cytosolic variants (m and c) for flatworm TGRs are shown. Grx domain active site and selenocysteine-containing TR domain are underlined.