Table 1.
Ratio of surface active agents and active pharmaceutical ingredients in formulated SMEDDS.
Composition | API (mg) | Ratio of Surface Active Agents in SMEDDSs (Total Volume of Composition: 1 mL) | ||||||
---|---|---|---|---|---|---|---|---|
Kolliphor RH40 | Labrasol | Capryol 90 | Lauroglycol FCC | Transcutol HP | Isopropyl Myristate | |||
1 | 0.001–0.05 | Cisplatin | 2 | 2 | 1 | 0 | 2 | 1 |
0.1–5.00 | Ifosfamide | 2 | 2 | 1 | 0 | 2 | 1 | |
0.0005–0.05 | Bleomycin sulfate | 2 | 2 | 1 | 0 | 2 | 1 | |
2 | 0.001–0.05 | Cisplatin | 2 | 2 | 1 | 0 | 4 | 1 |
0.1–5.00 | Ifosfamide | 2 | 2 | 1 | 0 | 4 | 1 | |
0.0005–0.05 | Bleomycin sulfate | 2 | 2 | 1 | 0 | 4 | 1 | |
3 | 0.001–0.05 | Cisplatin | 2 | 2 | 1 | 0 | 6 | 1 |
0.1–5.00 | Ifosfamide | 2 | 2 | 1 | 0 | 6 | 1 | |
0.0005–0.05 | Bleomycin sulfate | 2 | 2 | 1 | 0 | 6 | 1 | |
4 | 0.001–0.05 | Cisplatin | 1 | 1 | 0 | 1 | 1 | 1 |
0.1–5.00 | Ifosfamide | 1 | 1 | 0 | 1 | 1 | 1 | |
0.0005–0.05 | Bleomycin sulfate | 1 | 1 | 0 | 1 | 1 | 1 | |
5 | 0.001–0.05 | Cisplatin | 1 | 1 | 0 | 1 | 2 | 1 |
0.1–5.00 | Ifosfamide | 1 | 1 | 0 | 1 | 2 | 1 | |
0.0005–0.05 | Bleomycin sulfate | 1 | 1 | 0 | 1 | 2 | 1 | |
6 | 0.001–0.05 | Cisplatin | 1 | 1 | 0 | 1 | 4 | 1 |
0.1–5.00 | Ifosfamide | 1 | 1 | 0 | 1 | 4 | 1 | |
0.0005–0.05 | Bleomycin sulfate | 1 | 1 | 0 | 1 | 4 | 1 |