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(a) Chemical structure of dasatinib and [18F]SKI249380 (deoxy-[18F]fluoro-dasatinib); (b) Axial PET images representing the brain uptake for different nanoformulations of [18F]SKI249380 in a PDGFR-driven mouse model of high grade glioma. * p = 0.002, ** p = 0.014, *** p = 0.016. (reprinted from [132], with permission from Elsevier).
