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. 2015 Dec 9;20(12):22000–22027. doi: 10.3390/molecules201219816

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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(a) Chemical structures of recently identified and evaluated radiolabeked serine/threonine kinase inhibitors; (b) Chemical structure of [carbonyl-¹¹C]CEP-32496; (c) Brain PET images of [carbonyl-¹¹C]CEP-32496 in wild type (top panel) and P-gp/BCRP knockout mice (bottom panel) (reprinted from [160] © 2014, with permission from Elsevier); (d) Chemical structure of [¹¹C]alisertib.