Skip to main content
. 2015 Nov 19;20(11):20551–20568. doi: 10.3390/molecules201119717

Table 2.

PHD inhibitors developed by SBDD.

Compound Number Compound Structure IC50 Producer
1 graphic file with name molecules-20-19717-i001.jpg 2.4 μM Proctor & Gamble
2 graphic file with name molecules-20-19717-i002.jpg 0.017 μM Proctor & Gamble
3 (TM6008) graphic file with name molecules-20-19717-i003.jpg N/A Tokai University
4 (TM6089) graphic file with name molecules-20-19717-i004.jpg N/A Tokai University
5 (JNJ-42041935) graphic file with name molecules-20-19717-i005.jpg 0.1 μM Janssen
6 graphic file with name molecules-20-19717-i006.jpg 0.05 μM Janssen
7 graphic file with name molecules-20-19717-i007.jpg <25 μM Crystal-Genomics
8 graphic file with name molecules-20-19717-i008.jpg 2.1 μM Crystal-Genomics
9 graphic file with name molecules-20-19717-i009.jpg 0.003 μM Amgen