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. 2015 Sep 22;20(9):17570–17584. doi: 10.3390/molecules200917570

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© 2015 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Effects of crocetin (CCT) (panel A) and crocins (panel B) on the responses of aortic segments to increasing concentrations of phenylephrine in the presence or absence of indomethacin. Inset figure shows the effects of indomethacin alone on phenylephrine contractions. Inhibition of the cyclooxygenase pathway reduces contractions elicited by phenylephrine. * p < 0.05, ** p < 0.01 compared with the control curve.

Effects of crocetin (CCT) (panel A) and crocins (panel B) on the responses of aortic segments to increasing concentrations of phenylephrine in the presence or absence of indomethacin. Inset figure shows the effects of indomethacin alone on phenylephrine contractions. Inhibition of the cyclooxygenase pathway reduces contractions elicited by phenylephrine. * p < 0.05, ** p < 0.01 compared with the control curve.