Scheme 2. General Synthetic Routes Used to Prepare Compounds Based on the Pyridine-2-carboxylic Acid Scaffold.
(a) R1CO2H, HATU, Et3N, then LiOH; (b) R2SO2Cl, Et3N, then LiOH; (c) ArB(OH)2 and (Ph3P)4P, then LiOH; (d) R3NH2, HATU, Et3N, then LiOH.
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