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Chemical structures of the main secoiridoid constituents (nuzhenide and GL3) found in the Fraxinus angustifolia Vahl extract and of the specific metabolites detected in plasma and urine after the intake. The fragments originated from the hydrolysis of the secoiridoids are marked in red (tyrosol and ligstroside-aglycone). The derivatives produced by phase II conjugation are shown in blue color.
