Figure 2.

The micro-CT analysis of distal femur and proximal tibia in different groups. The sagittal (A) and transverse (B) views of micro-CT images showed the changes of osteoarthritic differences in subchondral bone structures of medial femoral and tibial compartments. The images with severe bone erosion, cyst and bone sclerosis were observed in OA and Articular cartilage groups, whereas T(M) group showed mild to moderate sclerotic bone formation which was due to bone remodeling and regeneration. The region of interesting (ROI) was indicated in red rectangle. The red arrow was indicated bone cyst. All rats were n=10.