. 2019 Jan 1;16(1):156–166. doi: 10.7150/ijms.26659

Table 1.

Pathological and micro-CT analysis.

Analysis		Sham	Meniscus	OA	T(M)	Articular cartilage
Pathological analysis
OA lesion score		0.00±0.00^bc	0.05±0.05^bc	3.40±0.20^ac	1.60±0.21^ab	3.00±0.23^ac
Maxima extension angle		19.12±1.65^b	19.91±1.87^b	59.36±9.04^ac	26.22±4.00^b	57.36±8.67^ac
BMD (g/cm²)		0.35±0.02^b	0.34±0.04^b	0.27±0.01^ac	0.34±0.03^b	0.29±0.02^ac
Medial Tibia lesion (%)		0.00±0.00^bc	0.00±0.00^bc	80.93±10.46^ac	55.43±8.32^ab	87.04±6.82^ac
Micro-CT analysis
Sb.Th (μm)	Femur	296.15±16.16	294.43±8.50	311.32±58.88	284.51±20.93	304.19±41.63
	Tibia	327.51±11.05^b	330.98±18.60	260.71±46.30^ac	332.41±20.55^b	301.66±50.00
BV/TV %	Femur	58.66±2.31^b	58.52±1.42^b	48.79±5.30^ac	59.29±4.63^b	50.27±4.24^ac
	Tibia	58.85±2.21^b	58.88±2.01^b	44.19±4.14^ac	62.59±2.44^b	45.65±3.66^ac
Tb.Th (μm)	Femur	149.75±4.74^c	143.82±5.64^c	157.48±21.20	164.58±7.37^a	162.54±20.57
	Tibia	146.07±8.50^bc	150.85±7.81^bc	193.65±17.06^a	187.85±13.35^a	200.87±19.27^a
Tb.N (1/mm)	Femur	4.03±0.22^bc	4.02±0.29^bc	2.97±0.53^a	3.35±0.26^a	2.60±0.41^ac
	Tibia	3.94±0.31^bc	4.04±0.40^bc	2.07±0.21^ac	2.89±0.38^ab	2.07±0.28^ac
Porosity (%)	Femur	41.34±2.07^b	41.48±1.27^b	51.21±4.74^ac	40.71±4.14^b	49.73±3.79^ac
	Tibia	41.15±2.21^b	41.12±2.01^b	55.81±4.14^ac	37.41±2.44^b	54.35±3.66^ac

Mean±SD obtained for all experimental groups with statistical results by one-way ANOVA, except OA lesion scores were expressed as mean ± SEM with statistical results by Kruskal-Wallis test. Statistical significance p < 0.05: a =Sham vs. other groups; b =OA vs. other groups; c = T(M) vs. other groups. Sb.Th=Subchondral plate thickness, BV= Bone volume, TV=Tissue volume, Tb.Th=Trabecular bone thickness, Tb.N=Trabecular bone number.