Table 1.
Blood electrolyte and chemical data of control Pkd2+/WS25 kidneys and cystic Pkd2WS25/- kidneys treated with vehicle or Sulindac. No statistically different was observed.
| control | PKD2+V | PKD2+SU | |
|---|---|---|---|
| Na (mEq/L) | 150±1.9 | 150±2.9 | 151±6.4 |
| K (mEq/L) | 4.2±0.4 | 4.6±0.8 | 4.9±0.8 |
| Cl (mEq/L) | 119±4.1 | 123±5.0 | 121±6.6 |
| Glu (mEq/L) | 185±48 | 180±35 | 225±94 |
| pH | 7.30±0.03 | 7.31±0.07 | 7.30±0.04 |
| TCO2 | 22±2.9 | 23±4.2 | 24±2.4 |
| BUN (mg/dl) | 21±3.9 | 26±5.8 | 26±7.2 |
| Hct (%) | 34±3.6 | 28±3.6 | 30±2.5 |
PKD2+V: PKD2WS25/-+vehicle; PKD2+SU: PKD2WS25/-+Sulindac