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. 2019 Jan 14;19:52. doi: 10.1186/s12879-018-3601-z

Fig. 5.

Fig. 5

Phosphorylated CREB expressing CD4+T cells in healthy individuals and leprosy patients. I Representative histogram showing CD4 + T cells expressing CREB in healthy individuals and leprosy patients. II Mean Percentage of pCREB expressing CD4+T cells in healthy individuals (H) and leprosy patients with or without stimulation with M. leprae antigens. PBMCs of different study subjects were incubated with medium only (A) or stimulated with MLSA, WCL and PGL-1antigens (B) and incubated for 24 h. After incubation cells were washed and stained with fluorescent labeled anti-CD3, anti-CD4, anti-pCREB and acquired in flow cytometer. * = p < 0.05 and ** = p < 0.001. BT/TT (Borderline tuberculoid/Tuberculoid), BL/LL (Borderline lepromatous/Lepromatous)