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. 2019 Jan 14;19:64. doi: 10.1186/s12885-018-5243-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Prognostic significance of the 4 core functional pathways (focal adhesion, PI3K-Akt signaling, HIF-1 signaling, and pluripotency of stem cells) in HNC patients, as determined by SurvExpress analysis from the TCGA-HNSCC dataset (n = 283). For each pathway, the log-rank test of the Kaplan-Meier survival curve for the risk group, the hazard ratio (HR) and the p-value (P) are shown