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. 2019 Jan 14;17:25. doi: 10.1186/s12967-019-1776-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — The protein–protein interaction analysis of the differentially expressed genes. Protein–protein interaction network of the module genes. Edge stands for the interaction between two genes. A degree was used for describing the importance of protein nodes in the network, red shows a high degree and blue presents a low degree. The significant two modules identified from the protein–protein interaction network shown with triangle (cluster 1) and diamond (cluster 2) using the molecular complex detection method with a score of > 6.0