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. 2019 Jan 14;20:24. doi: 10.1186/s12859-019-2601-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Correlation between AMYCO and pRANK predictions and the aggregation propensity of human hnRNPA2 prion-like protein variants. a Graphic representation of the correlation between the mutants' AMYCO (a) and pRANK (b) scores and their ability to form prionic colonies (Ade+) when expressed in yeast, a direct reporter of their aggregation propensity [13]